It has been said above, but just some more elaboration.

You must be aware of how deep your league is. You'll find yourself reading excellent articles describing a player that might break out for 50 points for example. Make sure there aren't 60 point players in FA first.

This goes for drafting too. I've been in one year leagues where people start picking this year's draft class in the first round. Very few of this year's draft class are going to be impactful in a 1 year league (assuming that it isn't absurdly deep).

Know your Categories. I generally play H2H format, but I was in a roto league where the goalie categories were W,L, GAA, SV%. (personally I think this setup was intrinsically flawed) Only one of those categories benefits from quantity of games. There was literally a manager who after the first week had a GAA of 1.1, a SV% over .95, and no losses. He never started another goalie, he finished last in Ws, but first in the other 3 categories and was able to use more roster spots on skaters.

Aside from that ridiculous example, i realized that I was never playing my 3rd goalie, because it was a league about quality starts not a quantity of starts.

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Yahoo H2H League: 12 Team, Full Keeper, 26 players plus farm team (3 round prospect draft, players<100gp)
G,A,P,+/,PIM,PPG,PPA,PPP,SHP,GWG,SOG,FW,W,Sv,Sv%,GA,GA%,SH O

Centers: Crosby, Duchene, Ribeiro, Weiss, Backlund, Shore
RW: Eberle, Voracek, Horton, Grabner, Atkinson
LW: Parise, Ovechkin, Moulson, Ennis, Tlusty, Boedker,
D: Shattenkirk, Carlson, Del Zotto, Barrie, Faulk
G: Pavelec, Varlamov, Lindback, Enroth

Farm: Lehner, Stalock, Salak, Yakupov, Rattie, Gudbranson, Josefson, Josi, Bjugstad