Going against popular opinion here, I'll take Byfuglien/Enstrom easily.

Enstrom has two 50+ point seasons under his belt and has 11 points in 8 games (leading all d-men) while Byfuglien has produced 53 points in both seasons he played D (not to mention last season he did it in 66 games - a 66 point pace) and has 7 points in 6 games this season (9th in D-scoring despite only 6 GP and on par with Karlsson despite 3 less GP).

So you can pretty much bank on the pairing hitting about 105+ points combined in an 82 game season assuming both are relatively healthy. Not to mention they've been arguably the two most effective offensive d-men in the league this year.

1) Buff/Enstom
2) AP/Shatty
3) Karlsson/Scrub