Well this is a very interesting draft you guys have. It's really tough to comment without knowing the structure of your farm system or your current team. If you take timeline completely out of the question and can sit on a big farm system for a long time then I'm taking McDavid at 3rd. At this point he's looking like a surefire number one overall with elite potential.
If, however, you're going to requre some NHL ready player in the next few years (lets say you active roster includes guys like Iginla, Datsyuk, etc) then I'm going for guys who'll be playing ASAP and that's Hubs and Schultz.
As for the comment from someone regarding Drouin being a late bloomer, that's not accurate. He was the 2nd overall pick in the 2011 QMJHL draft, right behind Mackinnon. His first year in Halifax he had an injury shortened regular season and still put up very solid numbers but absolutley exploded in the playoffs to become a major factor in the Mooseheads incredible playoff run (I was there for almost every game). This year he's been nothing short of spectacular and could emerge as the most offensively gifted player of the entire 2013 draft class. I'd have a very tough time deciding between him and Barkov but the X factor here is a player that really impressed me at the WJC.....Nichushkin! This kid is a manchild and looks like he could transition seamlessly into the NHL. That being said, I almost always steer clear of the Russian factor so that would probably eliminate him from the discussion for me.
As for Reinhart and Deschesne, I don't know enough to comment