I'll make some assumptions here:
*Points-Only (?)
*Start 3C/6W/4D (?)

I'd keep:
C - E. Staal, Kopitar, Benn
W - Kovalchuk, Giroux, Neal, St. Louis, Eriksson
D- Letang
G - Smith, Anderson, Dubnyk

This means (if it's my team), I'm considering dropping your 3 defensemen.
I don't know... I personally feel like there an absolute slew of 30-45pt defensemen out there.
Last year, I helped a buddy win his 13-team 6F/4D points-only pool... we went into the draft with just Karlsson.
Drafted 3D... and ended up replacing them ALL with waiver D during the year (guys like MDZ & Leddy).
Just piecing in some decent D-points allowed him to win the pool. [With Malkin, Datsyuk, Neal, Pavelski, E.Kane, Heatley, Karlsson + 3D, Fleury and Corey effin Crawford!]

Let's say you value the players as follows:
50pts: Letang
45pts: Shattenkirk
45pts: Enstrom
42pts: MDZ

The guy I'd look to move here is Letang.
Sure, you downgrade your defensemen, but what you gain in trade return on Letang (2nd rounder?) may be much higher than what you might get for ShattenK (4th rounder?) or Enstrom (5th rounder?). And, you only lose 5pts.


In other words... I think you should look to move one of your defensemen... whoever you can get the best return/draft-pick on.